The Ionization of Acidic Drug is Increased in Alkaline Urine and Ionized Drugs Cannot Easily Cross a Plasma Membrane

Image We are pleasure to introduce our Journal of Kidney Treatment and Diagnosis covers several clinical areas of renal medicine, such as dialysis, transplantation, diabetes, anaemia, pharmacy nutrition and clinical aspects of kidney care. Most diuretic drugs are either weak acids or weak bases. When urine is made alkaline, elimination of acidic drugs in the urine is increased. The converse applies for alkaline drugs. This method is only of the... Read More

Structural biology: Toxicology

Image Structural biology is a branch of molecular biology, biochemistry, and biophysics concerned with the molecular structure of biological macromolecules (especially proteins, made up of amino acids, RNA or DNA, made up of nucleotides, membranes, made up of lipids) how they acquire the structures they have, and how alterations in their structures affect their function.This subject is of great interest to biologists because macromolecules carry out most of the functions of cells, and it is only by coiling into specific three-dimensional shapes that they are able to perform these functions. This ... Read More

Molecularly Targeted therapy is one of the major modalities of Medical Treatment

Image Targeted therapy or molecularly targeted therapy is one of the major modalities of medical treatment (pharmacotherapy) for cancer, others being hormonal therapy and cytotoxic chemotherapy. As a form of molecular medicine, targeted therapy blocks the growth of cancer cells by interfering with specific targeted molecules needed for carcinogenesis and tumor growth, rather than by simply interfering with all rapidly dividing cells (e.g. with traditional chemotherapy). Because most agents for... Read More

Overview on: Pharmacogenomics

Image Pharmacogenomics is the study of the role of the genome in drug response. Its name (pharmaco- + genomics) reflects its combining of pharmacology and genomics. Pharmacogenomics analyzes how the genetic makeup of an individual affects his/her response to drugs. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with pharmacokinetics (drug absorption, distribution, metabolism, and elimination) and pharmacodynamics (effects mediated through a drug's biological targets). The te... Read More

Overview on: Pharmacovigilance

Image Pharmacovigilance (PV or PhV), also known as drug safety, is the pharmacological science relating to the collection, detection, assessment, monitoring, and prevention of adverse effects with pharmaceutical products. The etymological roots for the word "pharmacovigilance" are: pharmakon (Greek for drug) and vigilare (Latin for to keep watch). As such, pharmacovigilance heavily focuses on adverse drug reactions, or ADRs, which are defined as any response to a drug which is noxious and unintended, including lack of efficacy (the condition that this definition only applies with the do... Read More

The Techniques of Molecular Biology to study Protein function is Molecular Cloning

Image One of the most basic techniques of molecular biology to study protein function is molecular cloning. In this technique, DNA coding for a protein of interest is cloned using polymerase chain reaction (PCR), and/or restriction enzymes into a plasmid (expression vector). A vector has 3 distinctive features: an origin of replication, a multiple cloning site (MCS), and a selective marker usually antibiotic resistance. Locate... Read More

The Kidney is almost synonymous with renal clearance or renal plasma clearance

Image Journal of Kidney Treatment and Diagnosis consists of the latest findings related to pathogenesis and treatment of kidney disease, hypertension, acid-base and electrolyte disorders, dialysis therapies, and kidney transplantation. Pharmacokinetics studies the manner and speed with which drugs and their metabolites are eliminated by the various excretory organs. This elimination will be proportional to the drug's plasmatic concentrations. In order to model t... Read More

Pharmaceutical Technology-Open Access

Image Asian Journal of Pharmaceutical Technology and Innovation is a peer-reviewed, open access journal that reflects articles on all types of Drugs and Medicine. The journal welcomes submissions from all related fields of Pharmacy including advances in medicines. Articles will be also considered from related analysis from Drug Metabolism, Drug Delivery Systems, Drug Interactions, Drug Therapy, Drug Addiction, Pharmaceutical Industry, chemistry. Submission of important articles containing advanced research output aiding in forwarding the subject are most welcome. The wide scope of the j... Read More

New Techniques involved in Discovery of Medicine for Cancer

Image Cancer occurs when a single progenitor cell accumulates mutations and other changes in the DNA, histones, and other biochemical compounds that make up the cell's genome. The cell genome controls the structure of the cell's biochemical components, the biochemical reactions that occur within the cell, and the biological interactions of that cell with other cells.About 70 percent of pharmaceuticals are manufactured using palladium-driven catalytic processes that are either fast or efficient - bu... Read More

Calcium is Excreted in to the Intestine via the Bile

Image Journal of Kidney Treatment and Diagnosis consists of the latest findings related to pathogenesis and treatment of kidney disease, hypertension, acid-base and electrolyte disorders, dialysis therapies, and kidney transplantation. Calcium metabolism is the movement and regulation of calcium ions (Ca2+) in (via the gut) and out (via the gut and kidneys) of the body, and between body compartme... Read More

Transforming Pharmaceutical Drug Discovery and Development- Recent Technological Advances

Image The last decade has seen rapid technological progress but with increasing demands for safe and efficacious drugs, technological solutions that reduce the barriers to clinical success will be of more interest than those that simply shift the bottlenecks and necessitate new compromises in the discovery and development process. Numerous problem areas remain: better information relative to disease pathophysiology is needed to improve target selection and validation; more predictive, biologically-relevant high throughput screens are essential; and, more emphasis must be placed on acquiring good ... Read More

To be a medicine or a toxin? this is a question – a sphingolipid story

Image From being a medicine to be a toxin there is a step. This is true for many aspects: from the structure, to the effect and to the dosage. For example, myriocin (ISP-1), a potent immunosuppressant, is an analog of sphingosine, and an inhibitor of the enzyme serine palmitoyl transferase that generates sphingosine. However, when it comes to the physiological effect, myriocin inhibits the growth of a mouse cytotoxic T lymphocyte line whereas sphingosine completely suppresses the inhibitory effect. But while you may think sphingosine is “good”, and that more is better, high doses of s... Read More

Nanomedicine and biological microenvironment monitoring

Image Nanomedicine have gained increasing attention in recent years. Compared to small molecules, nanoparticles have many advantages in biomedical applications such as controlled drug delivery and therapy (by taking advantage of EPR effect). As a collection of atoms/molecules, nanoparticles exhibit much stronger absorbance and emissions compared to small molecular probes, which can provide improved local contrast in biological imaging and sensing applications. However, the toxicity of nanoparticles is a concern for clinical application. Nano systems that can simultaneously combine diagnosis, ther... Read More

Progenitor Carcinoma Stem Cell can be formed from Oncogenic Combinations of Mutations in a Totipotent Cell

Image Cancer occurs when a single progenitor cell accumulates mutations and other changes in the DNA, histones, and other biochemical compounds that make up the cell's genome. The cell genome controls the structure of the cell's biochemical components, the biochemical reactions that occur within the cell, and the biological interactions of that cell with other cells. Certain combinations of mutations in the given progenitor cell ultimately result in tha... Read More

Procedure involved in Laser lithotripsy

Image Laser lithotripsy is a surgical procedure to remove stones from urinary tract, i.e., kidney, ureter, bladder,or urethra. A urologist inserts a scope into the urinary tract to locate the stone. The scope may be a cystoscope, renoscope or nephroscope. An optical fiber is inserted through the working channel of the scope, and laser light is directly emitted to the stone. The stone is fragme... Read More

Asian Journal of Pharmaceutical Tecchnology and Innovation-Long Journey by Announcing Discounts on Article Processing Charges

Image The editorial team of Asian Journal of Pharmaceutical Technology and Innovation is overwhelmed by the response and eagerness of the academic and research contributors to publish with the journal and take part in the year-long celebrations. During this year we look forward to taking some initiates that would encourage and reward our prospective customers. It gives us great pleasure in announcing the call for paper on the 7th Anniversary of the Journal at special and hefty discount of up to 20 percent on one-time article processing charge. Prospective academicians an... Read More

Risk Factors Involved in Oncology

Image   Journal of Molecular Cancer  is an Open Access academic peer-reviewed journal, aimed at worldwide dissemination of scientific research in the field of Cancer. We are truly obliged to introduce our Journal as we are looking forward to framing up an outstanding inaugural issue with best quality research articles for great impact among the readers globally. Tobacco- The leading cause of cancer, and death from cancer. Smoking is associ... Read More

Streamlined process opens drug development to a new class of steroids.

Image Researchers at Dartmouth College have developed a technique to produce synthetic steroids that could pave the way for a cascade of new drug discoveries. The process facilitates access to rare, mirror-image isomers of naturally occurring steroid structures. The core molecular structure of steroids is a proven backbone in drug development. More than 100 different steroid molecules are approved by the U.S. Food and Drug Administration as therapeutics for a wide range of symptoms and diseases including inflammation and pain, cancer and bacterial infection. Steroidal therapeutics argua... Read More

Types of Hemodialysis

Image Journal of Kidney Treatment and Diagnosis consists of the latest findings related to pathogenesis and treatment of kidney disease, hypertension, acid-base and electrolyte disorders, dialysis therapies, and kidney transplantation. In hemodialysis, the patient's blood is pumped through the blood compartment of a dialyzer, exposing it to a partially permeable membrane. The dialyzer is composed of thousands of tiny hollow synthetic fibers. The f... Read More

The Single-Layer and Multi-Layer Drug-in-Adhesive Systems

Image Journal of Kidney Treatment and Diagnosis consists of the latest findings related to pathogenesis and treatment of kidney disease, hypertension, acid-base and electrolyte disorders, dialysis therapies, and kidney transplantation. A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream. Often,... Read More

Grooming the Pharmacological and toxicological Boundaries for Drug Discovery and Development

Image Journal of Clinical Pharmacology and Toxicology expresses gratitude to all its elite panel of editorial board members for their continuous efforts, support and encouragement throughout journey of the journal, right from its inception in the year 2018 and congratulates them for making the journal achieve its goals and becoming successful and well-recognized broadcaster of scientific outcomes and perspectives from systematic inquiry into infectious diseases, medici... Read More

Prescience of New Perceptions in the Field of Toxicology and Pharmacology

Image Journal of Clinical Pharmacology and Toxicology expresses gratitude to all its elite panel of editorial board members for their continuous efforts, support and encouragement throughout journey of the journal, right from its inception in the year 2018 and congratulates them for making the journal achieve its goals and becoming successful and well-recognized broadcaster of scientific outcomes and perspectives from systematic inquiry into infectious diseases, medici... Read More

Types of Transdermal Patches

Image Journal of Kidney Treatment and Diagnosis consists of the latest findings related to pathogenesis and treatment of kidney disease, hypertension, acid-base and electrolyte disorders, dialysis therapies, and kidney transplantation. A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream. Often, this promotes he... Read More

SCOPE OF PHARMACEUTICAL RESEARCH

Image Pharmacology and Toxicology Research, a peer reviewed, Open Access Journal provides an open platform for eminent scientists around the globe to publish their scholarly work in field related to organism association with their ecological niche and effects incurred by various deleterious toxic substances to organism and their effects at each level of ecological hierarchy. Various regulatory approaches for toxic chemicals management are included in scope of Journal o... Read More

Pharmacology and Toxicology: globalize your research work

Image Pharmacology and Toxicology Research, a peer reviewed, Open Access Journal provides an open platform for eminent scientists around the globe to publish their scholarly work in field related to organism association with their ecological niche and effects incurred by various deleterious toxic substances to organism and their effects at each level of ecological hierarchy. Various regulatory approaches for toxic chemicals management are included in scope of Journal o... Read More

Klotho Human Protein

Image  Journal of Kidney Treatment and Diagnosis consists of the latest findings related to pathogenesis and treatment of kidney disease,hypertension,acid-base and electrolyte disorders,dialysis therapies and kidney transplantation. Klotho is a naturally occurring human protein discovered in 1997. The name comes from the mythological Greek goddess, Klotho, who was one of the three Fates responsible for spinning the thre... Read More

Fibroblast Growth Factors their Functions

Image Journal of Kidney Treatment and Diagnosis consists of the latest findings related to pathogenesis and treatment of kidney disease, hypertension, acid-base and electrolyte disorders,dialysis therapies and kidney transplantation. The fibroblast growth factors (FGF) are a family of cell signaling proteins that are involved in a wide variety of processes, most notably as crucial elements for normal development. Any irregul... Read More

Evidence-based Toxicology | Pharmacology

Image Journal of Pharmacology and Toxicology Research, a peer reviewed, Open Access Journal provides an open platform for eminent scientists around the globe to publish their scholarly work in field related to organism association with their ecological niche and effects incurred by various deleterious toxic substances to organism and their effects at each level of ecological hierarchy. Various regulatory approaches for toxic chemicals management are included in scope o... Read More

Toxicology and Pharmaceutical Forensic Sciences

Image Journal of Pharmacology and Toxicology Research, a peer reviewed, Open Access Journal provides an open platform for eminent scientists around the globe to publish their scholarly work in field related to organism association with their ecological niche and effects incurred by various deleterious toxic substances to organism and their effects at each level of ecological hierarchy. Various regulatory approaches for toxic chemicals managem... Read More

Nanomedicine, bioimaging and biological microenvironment monitoring

Image Journal of Pharmacology and Toxicology Research, a peer reviewed, Open Access Journal provides an open platform for eminent scientists around the globe to publish their scholarly work in field related to organism association with their ecological niche and effects incurred by various deleterious toxic substances to organism and their effects at each level of ecological hierarchy. Various regulatory approaches for toxic chemicals management are included in scope o... Read More

(New) Drug Discovery: Multiple Trails Towards a Broadway

Image Journal of Pharmacology and Toxicology Research, a peer reviewed, Open Access Journal provides an open platform for eminent scientists around the globe to publish their scholarly work in field related to organism association with their ecological niche and effects incurred by various deleterious toxic substances to organism and their effects at each level of ecological hierarchy. Various regulatory approaches for toxic chemicals managem... Read More

Recent advances in the discovery of potential cancer-treating compounds.

Image On behalf of the Journal of Pharmaceutical Chemistry and Pharmacology, as Editor-In-Chief it is my great pleasure and honor to welcome you to the journal. A new study reports a novel method by which antitumor drugs that focus on reawakening exhausted immune cells called cytotoxic T cells against cancer can be quickly identified. This could help treat a large subset of cancers that thrive because of their ability to suppress antitumor activity in T c... Read More

Exploring Toxicological Mysteries for better life

Image Journal of Pharmacology and Toxicology Research, a peer reviewed, Open Access Journal provides an open platform for eminent scientists around the globe to publish their scholarly work in field related to organism association with their ecological niche and effects incurred by various deleterious toxic substances to organism and their effects at each level of ecological hierarchy. Various regulatory approaches for toxic chemicals management are included in scope o... Read More

Developing Drugs in Explore Novel Ideas

Image Journal of Pharmacology and Toxicology Research is a peer-reviewed Journal, encourages on-going international research and information exchange through publication of latest advances. The Journal is pleased to inform that it is been running successfully for 3 years and is running towards its 9th Anniversary. It is an Open access scholarly Developing Drugs. This journal is known for its quality research articles in the field of Pharmaceutics, Nanotechnology, Novel Drug Delivery Systems, Quality Control, Quality Assurance, International Regulatory, Validation Techniques, Industrial ... Read More

De Novo Advancements in Toxicology and Risk Assessment

Image Journal of Clinical Pharmacology and Toxicology expresses gratitude to all its elite panel of editorial board members for their continuous efforts, support and encouragement throughout journey of the journal, right from its inception in the year 2018 and congratulates them for making the journal achieve its goals and becoming successful and well-recognized broadcaster of scientific outcomes and perspectives from systematic inquiry into infectious diseases, medici... Read More

Unfold and Experience the Enigma in the World of Toxicology

Image Journal of Clinical Pharmacology and Toxicology expresses gratitude to all its elite panel of editorial board members for their continuous efforts, support and encouragement throughout journey of the journal, right from its inception in the year 2018 and congratulates them for making the journal achieve its goals and becoming successful and well-recognized broadcaster of scientific outcomes and perspectives from systematic inquiry into infectious diseases, medici... Read More

Journal of Pharmacology and Medicinal Chemistry-View on conferences

Image Journal of Pharmacology and Medicinal Chemistry aims to provide the most complete and reliable source of information on recent advancements in Pharmacology and Medicinal Chemistry. The emphasis will be on publishing quality articles rapidly and openly available to researchers, young scholars worldwide. Journal of Pharmacology and Medicinal Chemistry covers a broad spectrum of topics for study that discusses theoretical and conceptual aspects of Chemical ... Read More

Reviewer Invitation - Journal of Pharmacology and Medicinal Chemistry

Image Journal of Pharmacology and Medicinal Chemistry is an open access Peer-Reviewed journal that aims to publish the latest and outstanding Research articles, reviews, and letters in all the areas of Pharmacology and Medicinal Chemistry. We would like to invite you all eminent researches, scholars, medical students for the submission of articles which enhances our journal to the next level. We look forward to reading your next informative work in our Open Access journal so that it can reach ma... Read More

Trends in Clinical Pharmacology and Toxicology Research

Image Clinical Pharmacology and Toxicology Research is a peer-reviewed, open access journal that reflects articles on all types of chemically distinctive therapeutic and toxic agents. The journal welcomes submissions from all related fields to the Clinical pharmacology and Toxicology Research including clinical trials. Articles will be also considered from related analysis from Biochemical pharmacology, ... Read More

An overview of workflow process

Image Clinical Pharmacology and Toxicology Research Journal is a scientific journal aims to publish most complete and reliable source of information in the mode of original articles, review articles, case reports, short communications, Minireviews, letter to editor, commentaries, etc. Editorial or manuscript flow determines the overall process which each manuscript undergoes during the peer review process. The entire process of editorial workflow is main... Read More

Join our Editorial Board: Journal of Pharmacology and Medicinal Chemistry

Image Journal of Pharmacology and Medicinal Chemistry is one of the best Open Access journals publishes the relevant and reliable information on the discoveries and current developments and all other areas of the field and making them freely available online without any restrictions or any other subscriptions to researchers worldwide. The journal provides multi-disciplinary interpretation of the latest research advances in different aspects of therapeutic... Read More

Journal of Pharmacology and Medicinal Chemistry - Call for Papers

Image Journal of Pharmacology and Medicinal Chemistry is one of the best Open Access journals publishes the relevant and reliable information on the discoveries and current developments in the form of original articles, review articles, case reports, short communications, etc. and all other areas of the field and making them freely available online without any restrictions or any other subscriptions to researchers worldwide. Journal exp... Read More

Journal of Pharmaceutical Sciences and Drug Development: An Open Access Journal

Image Journal of Pharmaceutical Sciences and Drug Development has announced almost 50% discount on article processing charges (APC) to commemorate its 1st Anniversary. Editor-in-Chief David Gortler is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. Journal of Pharmaceutical Sciences and Drug Development solicits r... Read More

Field of Medicinal Chemistry

Image Medicinal chemists apply their chemistry coaching to the method of synthesizing new prescription drugs. They additionally improve the processes by that existing prescription drugs are created. medicative chemists are centered on drug discovery and development and are involved with the isolation of medicinal agents found in plants, still because the creation of latest artificial drug compounds. Most chemists work with a team of scientists from completely different disciplines, as well as biologists, toxicologists, pharmacologists, theoretical chemists, microbiologists, and biopharmacists. To... Read More

Instructions to Authors: Journal of Pharmacology and Medicinal Chemistry

Image Journal of Pharmacology and Medicinal Chemistry covers a broad spectrum of topics for study that discusses theoretical and conceptual aspects of Chemical Pharmacology, Chemical Biology of Molecules, Anti-Infective Agents in Medicinal chemistry, Pharmaceutical chemistry, Pharmaco-analysis, Pharmaceutical manufacturing, Medicinal organic c... Read More

Grooming the Pharmacological Boundaries for Drug Discovery and Development

Image Journal of Clinical Pharmacology and Toxicology expresses gratitude to all its elite panel of editorial board members for their continuous efforts, support and encouragement throughout journey of the journal, right from its inception in the year 2018 and congratulates them for making the journal achieve its goals and becoming successful and well-recognized broadcaster of scientific outcomes and perspectives from systematic inquiry into infectious diseases, medici... Read More

Sights and Insights into Pharmacology and Toxicology

Image   Journal of Clinical Pharmacology and Toxicology expresses gratitude to all its elite panel of editorial board members for their continuous efforts, support and encouragement throughout journey of the journal, right from its inception in the year 2018 and congratulates them for making the journal achieve its goals and becoming successful and well-recognized broadcaster of scientific outcomes and perspectives from systematic inquiry into infectious... Read More

Green chemistry to improve pharmaceutical manufacturing efficiency.

Image On behalf of the Journal of Pharmaceutical Chemistry and Pharmacology, as Editor-In-Chief it is my great pleasure and honor to welcome you to the journal. About 70 percent of pharmaceuticals are manufactured using palladium-driven catalytic processes that are either fast or efficient - but not both. Researchers at North Carolina State University have now developed a green chemistry method that combines aspects of both processes to improve efficiency... Read More

Journal of Pharmacology and Medicinal Chemistry: Features and Updates

Image Journal aims to provide the most complete and reliable source of information on recent advancements in Pharmacology and Medicinal Chemistry and providing the discount of 50% for the publication of the articles. The emphasis will be on publishing quality articles rapidly and openly available to researchers, young scholars worldwide. It is a great honor and pleasure for me to invite you to participate in this themed issue by contributing your unique idea for our forthcoming issues (volume3, issue1) in the form of research/review/case report/short communication/commentaries to our jo... Read More

Journal of Pharmacology and Medicinal Chemistry

Image Journal of Pharmacology and Medicinal Chemistry is an open access Peer-Reviewed journal that aims to publish the latest and outstanding Research articles, reviews, and letters in all the areas of Pharmacology and Medicinal Chemistry. It covers a broad range of topics including but not limited to Chemical Pharmacology, Chemical Biology of Molecules, Anti-Infective Agents in Medicinal chemistry, Pharmaceutical chemistry, Pharmaco-analysis, Pharmaceutical manufacturi... Read More

Journal of Clinical Pharmacology and Toxicology leading a Successful Journey of couple of years bonding with the Prominent authors to make a great impact in the Publishing Industry

Image Journal of Clinical Pharmacology and Toxicology expresses gratitude to all its elite panel of editorial board members for their continuous efforts, support and encouragement throughout journey of the journal, right from its inception in the year 2018 and congratulates them for making the journal achieve its goals and becoming successful and well-recognized broadcaster of scientific outcomes and perspectives from systematic inquiry into infectious diseases, medici... Read More

European Journal for Biomedical Informatics Shows High Respect to the Editors for Assisting Journal since 15 Years

Image On the grand occasion of competing 15th anniversary, European Journal for Biomedical Informatics (ISSN: 1801-5603) expresses gratitude to all the editorial board members for their continuous efforts, support and encouragement throughout the publication journey of the journal, right from its inception in the year 2005 and congratulates them for making the journal achieve its goals and becoming successful as one of the leading and well-recognized broadcaster of scientific outcomes and perspectives from systematic enquiry into Biom... Read More