The Application of First‑Trimester Volumetry in Predicting Pregnancy Complications

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Basic and Clinical Reproductive Sciences is an elite, highly cited, scientific open access journal that publishes peer reviewed, original research and review articles in the field of Reproductive science and medicine. The Journal aims to render a global platform for scientists and academicians to discuss and share numerous developments and issues related to Reproductive science. The journal provides multi-disciplinary interpretation of the latest research advances in different aspects of basic and clinical reproductive science and medicine, including basic reproductive biology, maternal-foetal medicine, obstetrics, gynaecology, gestation, reproductive endocrinology, uro-gynaecology, and embryology as research articles, review articles, short communications, short reports, book reviews, and letter to editor focussed on contemporary topics of reproductive medicine.

We are sharing one of the most cited article from our journal. Article entitled “The Application of First‑Trimester Volumetry in Predicting Pregnancy Complications” well written by Dr. TC Okeke.

Abstract

The application of first trimester volumetry in predicting pregnancy complications is a promising and interesting field in Obstetrics and Radiology. This was a descriptive review of first trimester volumetry in predicting pregnancy complications over a period of 6 months (January 1st, 2013 to June 30th, 2013). A search of literature on first trimester volumetry published in English was conducted. Relevant materials on first trimester volumetry were selected. Placenta volumes (PV) and embryo volume/fetal volume ratios in the first trimester are correlated with crown rump length (CRL) or gestational age (GA). Measurement of PV or placental quotient (PV/CRL ratio) is an early assessment to identify impaired trophoblast invasion and predict subsequent development of intrauterine growth restriction (IUGR) or pre‑eclampsia (PE). In early onset IUGR due to triploidy, or trisomy 13 or 18, a larger deficit in fetal volume is observed compared to CRL. In obstetric sonography, standardization of the 3D volumetric methodology is needed to improve reproducibility of measurement. The accuracy of these measurements is uncertain and current applicability to practice is not fully accepted, therefore, the current methods are yet to be standardized and general applicability is uncertain. Volumetry holds a good promise as an extra method for predicting IUGR, PE, aneuploidy, miscarriages, or stillbirth but lack of standardization currently limits its applicability.

Here is the link to view complete article: https://www.jbcrs.org/articles/the-application-of-firsttrimester-volumetry-in-predicting-pregnancy-complications.pdf

 

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